Treating an allergy's underlying
cause is the focus of sublingual immunotherapy (compared
to over-the-counter and prescription drugs, which provide relief from
symptoms).
One out of five Americans suffer from
allergies. For some, allergies are simply a short lived nuisance;
however for millions it’s a life altering disease. The only treatment
that reprograms the overreacting immune system is immunotherapy, this
involves gradual delivery of the substances that trigger allergies
to acclimate the body to the world around it.
Currently in the U.S. an estimate 3 million
people are in immunotherapy treatment. Almost all of these patients
are seen by allergists and are treated with injection immunotherapy.
In other parts of the world physicians
are expanding the use of immunotherapy by introducing the allergens
to the body through the cells lining the mouth, (oral mucosa). This
method is referred to as sublingual immunotherapy (SLIT). Up to seventy
five percent of allergy sufferers in southern Europe use antigen drops
under the tongue for their allergy treatment. According to a recent
review of over 20 European studies, patients who received allergy
drops experience a 42 % reduction in allergy symptoms and a 43% reduction
in medication use in less than 3 years.
Through it’s safety profile SLIT allows
patients who are not candidates for injection immunotherapy…children,
highly reactive patients, asthmatics, and those with food allergies...
to receive the benefits of immunotherapy. In our estimation, if those
who could benefits from SLIT were under treatment, the current 3 million
patients in immunotherapy would grow to 10-15 million.
Broader application, increased safety,
ease of use, higher compliance and cost are all advantages of SLIT